[Nichebabies] YOUR DETOX CENTRE NEEDS DETOXINGIs Year 2017 n Happy New Year! Tis the season for merriment and joy!As

YOUR DETOX CENTRE NEEDS DETOXING

Is Year 2017 n Happy New Year! Tis the season for merriment and joy!

As the food and drinks flow, take a moment to consider your hardworking liver. All the blood flow from the gastro-intestinal tract must flow to the liver before it passes through to the rest of the body. Not only does the liver receive food substances, it is also the first organ which gets hit by any toxin, chemical substances or inflammatory substances absorbed from the gut. That’s why our liver is indeed our body’s main detox centre.

But there is a limit to how much our liver can take. A sudden surge of toxin such as bingeing on alcohol can overwhelm the liver. Prolonged exposure to alcohol can slowly poison the liver too. The end result of liver injury is inflammation followed by fatty change in liver cells, cirrhosis and eventually, liver failure or even liver cancer.

While it is best to abstain from consuming alcohol, if it is impossible to avoid you should take steps to protect this vital organ from being injured by sudden binge drinking or prolonged drinking.

Alcohol injures the liver because it upsets the natural intestinal bacteria balance and results in a build-up of toxins produced by unhealthy intestinal bacteria. At the same time alcohol destroys the intestinal surface, allowing the toxins to easily cross over into the blood stream. The toxins go straight to the liver causing liver inflammation which progresses to fatty liver, cirrhosis and liver failure.

But there is an option available. LactoGG’s GG probiotic strain has been found to reduce liver injury due to alcohol.

How does LactoGG’s probiotic do it?

1. The “GG” probiotic breaks down the toxic end-product of alcohol called acetaldehyde.

2. It reduces inflammation of the stomach and intestinal surface caused by alcohol and promotes regeneration of injured intestinal cells. These protective effects help maintain a strong and intact intestinal surface barrier and prevent the absorption of toxins.

3. LactoGG’s probiotic bacteria in the gut promote the growth of many types of healthy bacteria despite the presence of alcohol. Having a wide variety of healthy intestinal bacteria is one of the keys to healthy intestinal function.

Because of LactoGG’s probiotic’s beneficial effects, studies have found that taking this probiotic before and after the consumption of alcohol has a direct anti-inflammatory effect on the liver. (Figure 1) If alcohol consumption has been going on over a long time, LactoGG’s probiotic REVERSES liver inflammation and fatty liver. During sudden consumption of large volumes of alcohol (binge drinking) LactoGG’s probiotic PREVENTS liver injury if the probiotic is taken before drinking. (Figure 2)

So when enjoying the festivities, spare a thought for your hardworking liver and take your friend, LactoGG, with you to the parties!

Reference:

Keshavarzian A et al. Leaky gut in alcoholic cirrhosis:a possible mechanism for alcohol-induced liver damage. Am J Gastroenterol 1999;94:200-207

Mutlu E et al. Intestinal dysbiosis: a possible mechanism of alcohol-indued endotoxemia and alcoholic setateohepatitis in rats. Alcohol Clin Exp REs 2009;33:1836-1846

Bode C et al. Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess. J Hepatol 1987;4:8-14
Nosova T. Acetaldehyde production and metabolism by human indigenous and probiotic Lactobacillus and Bifidobacterium strains. Alcohol Alcohol 2000;35(6):561-568

Wang Y et al. Lactobacillus rhamnosus GG treatment potentiates intestinal hypoxia-inducible factor, promotes intestinal integrity and ameliorates alcohol-induced liver injury. Am J Pathol 2011;179:2866-2875

Donato KA et al. Lactobacillus rhamnosus GG attenuates interferon-ɣ and tumor necrosis factor-ɑ-induced barrier dysfunction and pro-inflammatory signalling. Microbiology 2010 July 23;doi:10.1099/mic.0.040139-0

Yan F et al. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology 2007;132:562-75

Lam EKY et al. Enhancement of gastric mucosal integrity by Lactobacillus rhamnosus GG. Life Sciences 2007;80:2128-36

Forsyth CB et al. Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis. Alcohol 2009;43(2):163-172

Wang Y et al. Lactobacillus rhamnosus GG culture supernatant ameliorates acute alcohol-induced intestinal permeability and liver injury. Am J Physiol Gastrointest Liver Physiol 2012;doi:10.1152/aj[gi.00024.2012

Adawi D et al. Effects of different probiotic strains of Lactobacillus and Bifidobacterium on bacterial translocation and liver injury in an acute liver injury model. Int J Food Microbiol 2001;70:213-220

Nanji AA et al. Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease). Proc Soc Exp Biol Med 1994;205(3):243-247

Bajaj JS et al. Randomized clinical trial: lactobacillus gg modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis. Aliment Pharmacol Ther 2014;39(10):1113-25

Bull-Otterson L et al - Metagenomic Analyses of Alcohol Induced Pathogenic Alterations in the Intestinal Microbiome and the Effect of Lactobacillus rhamnosus GG Treatment. PLoS ONE 8(1):e53028.doi:10.1371/journal.pone.0053028


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23 Jan 2017 BQ’s Daily Top Deals: iChef Warehouse Sale, Cotton On 38% OFF, Qoo10 Up to $88 Cart Coupons, Foodpanda 20% OFF, AirAsia ASEAN & Beyond Sale, $3 OFF GrabShare Rides & More!

BQ's Daily Top Deals: iChef Warehouse Sale, Cotton On 38% OFF, Qoo10 Up to $88 Cart Coupons, Foodpanda 20% OFF, AirAsia ASEAN & Beyond Sale, $3 OFF GrabShare Rides & More!
Local Posted 24 hours ago

Just a few more days to CNY! Have you prepared for the reunion dinner? If not, head to iChef Warehouse Sale or Cold Storage to grab some of their reunion ingredients on sale!

If you do not have time, why not order food delivery with Foodpanda? Get 20% off all Chinese cuisine this week with coupon code!

Also do a bit of last minute shopping at Cotton On CNY Sale with 38% off, Qoo10 with up to $88 cart coupons or mark your calendar for the upcoming The Hour Glass Special Timepiece Sale to get that watch that you have always wanted.

Book your holiday at AirAsia's ASEAN and Beyond Sale and use the coupon code for $3 off Grabshare rides!

 

 

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Book by 29 Jan 2017 AirAsia: Fly to ASEAN & Beyond from Only SGD0.18!

AirAsia: Fly to ASEAN & Beyond from Only SGD0.18!
Local Posted 1 day ago

Fly to ASEAN and beyond on the World's Leading Low-Cost Airline! AirAsia is offering fares to Cebu, Jakarta, Krabi, Penang, Phuket, Yogyakarta, Mauritius, Osaka, Seoul, Wuhan and many more destinations from SGD0.18 (base fare)!

Book before 29 Jan for immediate travel!

(more…)

Till 26 Jan 2017 Cold Storage: 4-Day Sale on Your Festive Dinner Needs

Cold Storage: 4-Day Sale on Your Festive Dinner Needs
Local2017 Chinese New Year Posted 1 day ago

If you are preparing for your CNY reunion dinner, check out Cold Storage's 4-Day sale on steamboat ingredients such as scallops, tiger prawns, sea cucumbers, cuttlefish/prawn balls, wontons and more!

 

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Daily Till 25 Jan 2017 Qoo10: Up to $88 Cart Coupons Up for Grabs and CNY Super Sale!

Qoo10: Up to $88 Cart Coupons Up for Grabs and CNY Super Sale!
Local Posted 1 day ago

From today till 25 January 2017 daily, grab cart coupons up to $88 at Qoo10 to save on your purchases!

Also find deals on Kate Spade wallets, New Moon abalones, Lancome Cushion Compacts, Mei Xin Star Wars cookies and more!

 

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Till 26 Jan 2017 iChef: CNY Warehouse Sale Up to 50% OFF Snow Crabs, Scallops, Shrimps, Clams and More!

iChef: CNY Warehouse Sale Up to 50% OFF Snow Crabs, Scallops, Shrimps, Clams and More!
Local2017 Chinese New Year Posted 1 day ago

USHER IN THE YEAR OF ROOSTER WITH iChef WAREHOUSE SALE! So what are you waiting for? Come down and choose from a wide selection of premium restaurant-grade ingredients to enjoy this Lunar New Year!

Enjoy up to 50% off snow crabs, scallops, shrimps, clams and more! Last few days, so hurry!

 

(more…)

Till 26 Jan 2017 Grab: $3 OFF Your GrabShare Ride

Grab: $3 OFF Your GrabShare Ride
Local Posted 1 day ago

Back by popular demand! Enjoy $3 OFF your GrabShare ride with promo code. Valid from 21 to 26 Jan, between 10am and 10pm, when you pay with your card. Hurry, limited redemptions only!

 

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30 Jan 2017 UberEATS: FREE Hai Di Lao Hot Pot Sets for Standard Chartered Card Holders & New Users

UberEATS: FREE Hai Di Lao Hot Pot Sets for Standard Chartered Card Holders & New Users
Local2017 Chinese New Year Posted 3 hours ago

To celebrate Chinese New Year, UberEATS is bringing a hot pot set comprising S$300 worth of food straight to your doorstep. This on-demand service will be available for one day only - on Monday, Jan 30. This delivery will be free for Standard Chartered card holders and new users of UberEATS. It will cost $88 for everyone else.

 

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24 Jan 2017 NTUC FairPrice: Special ONE-DAY Only Deals

NTUC FairPrice: Special ONE-DAY Only Deals
LocalLast Day Posted 14 hours ago

Head to the NTUC FairPrice store nearest to you now to grab these special One-Day Only deals! #StretchYourDollar and take your pick from festive essentials like Essence of Chicken for gifting, mandarins for visiting, shrimp wontons for steamboating and many more!

This promotion is limited to TODAY ONLY, so get yours in time!

 

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24 Jan 2017 Sheng Siong: Special One-Day Only Deals!

Sheng Siong: Special One-Day Only Deals!
Local2017 Chinese New Year Posted 4 hours ago

Head to the Sheng Siong store nearest to you now to grab these special One-Day Only deals! Save up to 51% on Yeo's Soya Bean, wild abalones, Ferrero Rochers, 100PLUS canned drinks, lukans and more!

 

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27 - 31 Jan 2017 Starhub: FREE Preview of Over 150 Starhub Channels

Starhub: FREE Preview of Over 150 Starhub Channels
Local2017 Chinese New Year Posted 5 hours ago

Now you can binge on all your favourite CNY goodies AND binge watch your favourite TV shows! Starhub is giving all their customers free preview of over 150 StarHub channels from 27 Jan, noon onwards to 31 Jan, noon. Gong Xi Fa Cai! 

 

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25 - 31 Jan 2017 Singtel: FREE Preview of Up to 150 Channels on Singtel TV and Singtel TV GO

Singtel: FREE Preview of Up to 150 Channels on Singtel TV and Singtel TV GO
Local2017 Chinese New Year Posted 2 days ago

Celebrate Chinese New Year with a FREE preview of up to 150 channels on Singtel TV and Singtel TV GO! From 25-31 Jan, existing Singtel TV subscribers can enjoy a free preview of the best of Asian blockbusters, U.S. TV series and Hollywood movies. Huat ah! (more…)

Till 25 Jan 2017, 1700hrs HipVan: Coupon Code for $18 OFF Last Minute CNY Must-Haves

HipVan: Coupon Code for $18 OFF Last Minute CNY Must-Haves

Grab these quirky last minute CNY deco at HipVan! Enjoy $18 off with a min. purchase of $80 at HipVan with this coupon code! Order by 25 January 2017, 1700hrs for the items to arrive in time for Chinese New Year.

 

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Till 29 Jan 2017 The Manhattan FISH MARKET: Calamari Mussels Chicken Set Inclusive of a Drink at just $9.95 for a Limited Time Only!

The Manhattan FISH MARKET: Calamari Mussels Chicken Set Inclusive of a Drink at just $9.95 for a Limited Time Only!
Local Posted 23 hours ago

Have the best of both poultry and seafood with The Manhattan FISH MARKET's Calamari Mussels Chicken Set (comes with a drink) from now till 29th Jan at just $9.95! Simply flash this image when ordering to enjoy. Valid islandwide except Changi Airport T1.

 

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Till 31 Jan 2017 Miam Miam French.Japanese Cafe.Kitchen: FREE Main Course for Those Born in the Year of Rooster

Miam Miam French.Japanese Cafe.Kitchen: FREE Main Course for Those Born in the Year of Rooster
Local Posted 1 day ago

If you are born in the year of Rooster, come enjoy a main course absolutely free at Miam Miam  between now to 31 January! Just come with three other of your friends!

Not born in the year of Rooster? Fret not because the criteria changes every week!

 

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4 - 7 Feb 2017 The Hour Glass: Special Timepiece Sale

The Hour Glass: Special Timepiece Sale
Local Posted 1 day ago

Get your hands on that exquisite timepiece that you've been eyeing this Lunar New Year! The Hour Glass is hosting a special sale at Raffles Hotel Singapore from 4- 7 Feb 2017. Mark the date on your calendar and visit them before time runs out!

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Limited time only! Watsons: Enjoy $3 OFF on All Cosmetics Products with Min. Spend of $28!

Watsons: Enjoy $3 OFF on All Cosmetics Products with Min. Spend of $28!
Local Posted 10 hours ago

Enjoy $3 Off with every min. nett spend of $28 on any cosmetics products at Watsons! Discount is on top of existing in-store promotion. (more…)

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