[Nichebabies] YOUR DETOX CENTRE NEEDS DETOXINGIs Year 2017 n Happy New Year! Tis the season for merriment and joy!As

YOUR DETOX CENTRE NEEDS DETOXING

Is Year 2017 n Happy New Year! Tis the season for merriment and joy!

As the food and drinks flow, take a moment to consider your hardworking liver. All the blood flow from the gastro-intestinal tract must flow to the liver before it passes through to the rest of the body. Not only does the liver receive food substances, it is also the first organ which gets hit by any toxin, chemical substances or inflammatory substances absorbed from the gut. That’s why our liver is indeed our body’s main detox centre.

But there is a limit to how much our liver can take. A sudden surge of toxin such as bingeing on alcohol can overwhelm the liver. Prolonged exposure to alcohol can slowly poison the liver too. The end result of liver injury is inflammation followed by fatty change in liver cells, cirrhosis and eventually, liver failure or even liver cancer.

While it is best to abstain from consuming alcohol, if it is impossible to avoid you should take steps to protect this vital organ from being injured by sudden binge drinking or prolonged drinking.

Alcohol injures the liver because it upsets the natural intestinal bacteria balance and results in a build-up of toxins produced by unhealthy intestinal bacteria. At the same time alcohol destroys the intestinal surface, allowing the toxins to easily cross over into the blood stream. The toxins go straight to the liver causing liver inflammation which progresses to fatty liver, cirrhosis and liver failure.

But there is an option available. LactoGG’s GG probiotic strain has been found to reduce liver injury due to alcohol.

How does LactoGG’s probiotic do it?

1. The “GG” probiotic breaks down the toxic end-product of alcohol called acetaldehyde.

2. It reduces inflammation of the stomach and intestinal surface caused by alcohol and promotes regeneration of injured intestinal cells. These protective effects help maintain a strong and intact intestinal surface barrier and prevent the absorption of toxins.

3. LactoGG’s probiotic bacteria in the gut promote the growth of many types of healthy bacteria despite the presence of alcohol. Having a wide variety of healthy intestinal bacteria is one of the keys to healthy intestinal function.

Because of LactoGG’s probiotic’s beneficial effects, studies have found that taking this probiotic before and after the consumption of alcohol has a direct anti-inflammatory effect on the liver. (Figure 1) If alcohol consumption has been going on over a long time, LactoGG’s probiotic REVERSES liver inflammation and fatty liver. During sudden consumption of large volumes of alcohol (binge drinking) LactoGG’s probiotic PREVENTS liver injury if the probiotic is taken before drinking. (Figure 2)

So when enjoying the festivities, spare a thought for your hardworking liver and take your friend, LactoGG, with you to the parties!

Reference:

Keshavarzian A et al. Leaky gut in alcoholic cirrhosis:a possible mechanism for alcohol-induced liver damage. Am J Gastroenterol 1999;94:200-207

Mutlu E et al. Intestinal dysbiosis: a possible mechanism of alcohol-indued endotoxemia and alcoholic setateohepatitis in rats. Alcohol Clin Exp REs 2009;33:1836-1846

Bode C et al. Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess. J Hepatol 1987;4:8-14
Nosova T. Acetaldehyde production and metabolism by human indigenous and probiotic Lactobacillus and Bifidobacterium strains. Alcohol Alcohol 2000;35(6):561-568

Wang Y et al. Lactobacillus rhamnosus GG treatment potentiates intestinal hypoxia-inducible factor, promotes intestinal integrity and ameliorates alcohol-induced liver injury. Am J Pathol 2011;179:2866-2875

Donato KA et al. Lactobacillus rhamnosus GG attenuates interferon-ɣ and tumor necrosis factor-ɑ-induced barrier dysfunction and pro-inflammatory signalling. Microbiology 2010 July 23;doi:10.1099/mic.0.040139-0

Yan F et al. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology 2007;132:562-75

Lam EKY et al. Enhancement of gastric mucosal integrity by Lactobacillus rhamnosus GG. Life Sciences 2007;80:2128-36

Forsyth CB et al. Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis. Alcohol 2009;43(2):163-172

Wang Y et al. Lactobacillus rhamnosus GG culture supernatant ameliorates acute alcohol-induced intestinal permeability and liver injury. Am J Physiol Gastrointest Liver Physiol 2012;doi:10.1152/aj[gi.00024.2012

Adawi D et al. Effects of different probiotic strains of Lactobacillus and Bifidobacterium on bacterial translocation and liver injury in an acute liver injury model. Int J Food Microbiol 2001;70:213-220

Nanji AA et al. Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease). Proc Soc Exp Biol Med 1994;205(3):243-247

Bajaj JS et al. Randomized clinical trial: lactobacillus gg modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis. Aliment Pharmacol Ther 2014;39(10):1113-25

Bull-Otterson L et al - Metagenomic Analyses of Alcohol Induced Pathogenic Alterations in the Intestinal Microbiome and the Effect of Lactobacillus rhamnosus GG Treatment. PLoS ONE 8(1):e53028.doi:10.1371/journal.pone.0053028


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20 - 24 Feb 2017 Grab: Coupon Code for $5 OFF Your GrabTaxi Ride

Grab: Coupon Code for $5 OFF Your GrabTaxi Ride
Local Posted 2 days ago

Whether you’re the type to commute early in the mornings or are on the move all day, GrabTaxi has got your back!

From Monday until Friday, all early birds that ride from 6am-8am, get $6 off using this promo code! If you’re a busy bee, travel with GrabTaxi from 11am-11pm at $5 off by using the below promo code! Limited redemptions per day.

 

(more…)

20 - 24 Feb 2017 Starbucks: Flash This to Get 1-for-1 Drink This Week!

Starbucks: Flash This to Get 1-for-1 Drink This Week!
Local Posted 2 days ago

The coffee-go-round: where bearistas have endless coffee and pandas show-off their smooth moves.

Just flash the screen grab of two Starbucks cups in stores for a one-for-one treat! Valid from 20-24 Feb, on all handcrafted drinks, all sizes. Limited to 2 redemptions per transaction. T&Cs apply. (more…)

20 - 28 Feb 2017 NTUC Warehouse Club: Open to All Renovation Clearance Sale Up to 90% OFF

NTUC Warehouse Club: Open to All Renovation Clearance Sale Up to 90% OFF
Local Posted 1 day ago

Warehouse Club (WHC) is a membership based warehouse retail club. Opened in December 2014, It is the first and only warehouse club in Singapore for groceries and household consumables. WHC members enjoy greater savings through bulks buys, value packs and exclusive access to direct import products.

Before they undergo renovation, they are having a Open to All Renovation Clearance Sale with up to 90% off storewide! No membership required so hurry down now! Sale ends on 28 February 2017.

 

(more…)

20 - 24 Feb 2017 Grab: Coupon Code for $6 OFF Your GrabTaxi Ride Between 6am to 8am

Grab: Coupon Code for $6 OFF Your GrabTaxi Ride Between 6am to 8am
Local Posted 2 days ago

Whether you’re the type to commute early in the mornings or are on the move all day, GrabTaxi has got your back!

From Monday until Friday, all early birds that ride from 6am-8am, get $6 off using the below promo code! If you’re a busy bee, travel with GrabTaxi from 11am-11pm at $5 off by using this promo code. Limited redemptions per day.

 

(more…)

Dining Coupons – Feb/Mar 2017

Dining Coupons - Feb/Mar 2017
Local Posted 7 hours ago

BQ knows how important every little saving is, that's why dining coupons are so important! Especially when fast food and restaurants are getting more and more expensive. Here's all the latest dining coupons for February and March 2017 consolidated for your easy access! Remember to stay updated on the latest coupons at BQ.sg and at our Facebook page!

 

(more…)

Cathay Cineplexes: Grab A Pair of Tickets @ $15 Only!

Cathay Cineplexes: Grab A Pair of Tickets @ $15 Only!
Local Posted 7 hours ago

Don't miss out on Cathay Cineplexes' limited period offer! Buddy up and catch a movie with your friend at only $15 for a pair of tickets from Monday to Thursday. Top up $5 for a large popcorn & 2 soft drinks at the box office! You can now save up to $11.80 easily - grab it before it’s gone!

 

(more…)

22 Feb 2017 Courts: 22.2 Febulous 1-Day Online Sale – Up to 85% OFF + Up to $202 OFF with Coupon Codes

Courts: 22.2 Febulous 1-Day Online Sale - Up to 85% OFF + Up to $202 OFF with Coupon Codes
Local Posted 4 hours ago

THE BIGGEST COURTS ONLINE SALE IS NEAR! 22.2 Febulous 1-Day Online Sale will be featuring the greatest deals on this side of the internet with jaw-dropping, unbeatable prices with savings of up to 85%! Fastest fingers first! So get ready to grab the deals on 22 February 2017! Also get up to $202 off with coupon codes!

 

(more…)

Book by 26 Feb 2017 AirAsia: Airfare Promotion to Bali, Cebu, Penang, Phuket and more from just $5!

AirAsia: Airfare Promotion to Bali, Cebu, Penang, Phuket and more from just $5!
Local Posted 5 hours ago

Embark on your new adventures to Bali, Cebu, Penang, Phuket and more from just $5 on AirAsia! Book before 26 Feb!

 

(more…)

Limited time only! Timberland: Online Exclusive Sale – 40% OFF Footwear +Additional 15% OFF with Coupon Code!

Timberland: Online Exclusive Sale - 40% OFF Footwear +Additional 15% OFF with Coupon Code!
Local Posted 3 hours ago

Grab a pair of quality boots from Timberland now online with their 40% off footwear sale! Limited sizes available while stocks last so hurry! Also get additional 15% off when you spend min. $150 with this coupon code!

 

(more…)

From 22 Feb 2017 Starbucks: NEW Tahitian Vanilla Macchiato and Valencia Orange Cocoa Cappuccino

Starbucks: NEW Tahitian Vanilla Macchiato and Valencia Orange Cocoa Cappuccino
Local Posted 3 hours ago

Time to try Starbucks' new drinks Tahitian Vanilla Macchiato and Valencia Orange Cocoa Cappuccino from 22 February!

 

(more…)

Till 26 Feb 2017 Esprit: Spring New Arrival Promotion – 25% OFF Storewide + Extra 10% OFF Sale Items (Min. 2)

Esprit: Spring New Arrival Promotion - 25% OFF Storewide + Extra 10% OFF Sale Items (Min. 2)
Posted 5 hours ago

Exclusively for Esprit Friends, enjoy new arrivals and everything else at 25% off and sale items (min. 2pcs) at extra 10% off!

If you are not an Esprit Friend yet, just sign up free online when you check out! Sale ends 26 February 2017.

 

*Terms and conditions applied, please refer to ESPRIT official website for reference. In case of any dispute, the decision of ESPRIT shall be final.

 

(more…)

Till 31 Dec 2017 Cathay Cineplexes: Enjoy $5 OFF Movie Tickets with Your Pet Lovers Centre Card!

Cathay Cineplexes: Enjoy $5 OFF Movie Tickets with Your Pet Lovers Centre Card!
Local Posted 6 hours ago

Flash your Pet Lovers Centre card to enjoy $5 off a pair of movie tickets from now till 31 December 2017 at Cathay Cineplexes!

 

(more…)

20 - 21 Feb 2017 BQ’s Daily Top Deals: $6 OFF GrabTaxi Ride, NTUC Warehouse Club Renovation Sale, $5 OFF Movie Tickets, Courts 22.2 Online Sale, Esprit 25% OFF & More!

BQ's Daily Top Deals: $6 OFF GrabTaxi Ride, NTUC Warehouse Club Renovation Sale, $5 OFF Movie Tickets, Courts 22.2 Online Sale, Esprit 25% OFF & More!
Local Posted 24 mins ago

 

This week get up to $6 off your GrabTaxi ride with this coupon code as well as discounts off movie tickets from Cathay Cineplexes!

Head to NTUC Warehouse Club for their Open House to All Renovation Sale and enjoy up to 90% off your grocery shopping!

Other offers include: AirAsia airfare promotion from $5, Courts 22.2 Febulous 1-Day Online Sale, New Starbucks drinks and Esprit sale with 25% off storewide!

 

(more…)

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